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Office Space for Sale in Central Florida

Browse live office and medical-office listings across Central Florida — multi-tenant buildings, professional condos, and medical pads — pulled straight from Stellar MLS, no Crexi or LoopNet detour. Filter by price, building size, and submarket, then take the search to the map.

733 active lease listings right now.

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654 MuñOz Rivera, PR654 MuñOz Rivera, PR
Stellar MLS
ActiveOffice360°

$9.46M /mo

654 MuñOz Rivera

San Juan, PR 00918

1.7 ac · Built 1980

654 MuñOz Rivera

MLS #PR9118208, WINER PROPERTY GROUP.

Listing provided by Stellar MLS

250 MuñOz Rivera, PR250 MuñOz Rivera, PR
Stellar MLS
ActiveOffice360°

$8.48M /mo

250 MuñOz Rivera

San Juan, PR 00918

0.8 ac · Built 1985

American International Plaza

MLS #PR9118209, WINER PROPERTY GROUP.

Listing provided by Stellar MLS

270 MuñOz Rivera, PR270 MuñOz Rivera, PR
Stellar MLS
ActiveOffice360°

$6.22M /mo

270 MuñOz Rivera

San Juan, PR 00918

1.5 ac · Built 1998

270 MuñOz Rivera

MLS #PR9118201, WINER PROPERTY GROUP.

Listing provided by Stellar MLS

252 Ponce De Leon Ave, PR252 Ponce De Leon Ave, PR
Stellar MLS
ActiveOffice360°

$2.60M /mo

252 Ponce De Leon Ave

San Juan, PR 00918

1.23 ac · Built 1973

City Towers

MLS #PR9095901, WINER PROPERTY GROUP.

Listing provided by Stellar MLS

650 MuñOz Rivera, PR650 MuñOz Rivera, PR
Stellar MLS
ActiveOffice

$2.16M /mo

650 MuñOz Rivera

San Juan, PR 00918

1 ac · Built 1980

650 MuñOz Rivera

MLS #PR9118207, WINER PROPERTY GROUP.

Listing provided by Stellar MLS

1510 F. D. Roosevelt Ave., PR1510 F. D. Roosevelt Ave., PR
Stellar MLS
ActiveOffice

$1.47M /mo

1510 F. D. Roosevelt Ave.

Guaynabo, PR 00965

0.8 ac · Built 1990

Triple S Plaza

MLS #PR9118220, WINER PROPERTY GROUP.

Listing provided by Stellar MLS

300 Avenida Las Cumbres, PR300 Avenida Las Cumbres, PR
Stellar MLS
ActiveOffice360°

$1.44M /mo

300 Avenida Las Cumbres

San Juan, PR 00926

5 ac · Built 1990

Las Vistas Shopping Village

MLS #PR9118212, WINER PROPERTY GROUP.

Listing provided by Stellar MLS

17215 Grassy Lake Rd, FL17215 Grassy Lake Rd, FL
Stellar MLS
ActiveOffice

$1.43M /mo

17215 Grassy Lake Rd

Minneola, FL 34715

31,879 SF · 4.46 ac · Built 2026

MLS #O6281617, ALBEKORD, INC..

Listing provided by Stellar MLS

1620 Tamiami Trl, FL1620 Tamiami Trl, FL
Stellar MLS
ActiveOffice360°

$885K /mo

1620 Tamiami Trl

Port Charlotte, FL 33948

49,172 SF · 3.24 ac · Built 1992

MLS #A4678188, RE/MAX ALLIANCE GROUP.

Listing provided by Stellar MLS

6550 W Hillsborough Ave, FL6550 W Hillsborough Ave, FL
Stellar MLS
ActiveOffice360°

$690K /mo

6550 W Hillsborough Ave

Tampa, FL 33634

156,648 SF · 14.73 ac · Built 1999

Tom Sawyer Sub

MLS #TB8490633, ONEIL COMMERCIAL ADVISORS.

Listing provided by Stellar MLS

7402 N 56th St St, FL7402 N 56th St St, FL
Stellar MLS
ActiveOffice360°

$400K /mo

7402 N 56th St St

Tampa, FL 33617

10.71 ac · Built 1975

MLS #R4906701, RS EQUITY SERVICE LLC.

Listing provided by Stellar MLS

5623 Us-19 N Hwy, FL5623 Us-19 N Hwy, FL
Stellar MLS
ActiveOffice

$400K /mo

5623 Us-19 N Hwy

New Port Richey, FL 34652

1.21 ac · Built 1974

MLS #R4906703, RS EQUITY SERVICE LLC.

Listing provided by Stellar MLS

1107 W Marion Ave, FL1107 W Marion Ave, FL
Stellar MLS
ActiveOffice360°

$395K /mo

1107 W Marion Ave

Punta Gorda, FL 33950

23,689 SF · 2 ac · Built 2001

Punta Gorda

MLS #C7504508, MAXIM COMMERCIAL REAL ESTATE,.

Listing provided by Stellar MLS

3300 Henderson Blvd #202, 203, FL
Stellar MLS
ActiveOffice

$376K /mo

3300 Henderson Blvd #202, 203

Tampa, FL 33609

16,528 SF · 0.76 ac · Built 1971

Southern Pines

MLS #TB8455053, SMITH & ASSOCIATES REAL ESTATE.

Listing provided by Stellar MLS

3130 Us Highway 1 S, FL3130 Us Highway 1 S, FL
Stellar MLS
ActiveOffice360°

$371K /mo

3130 Us Highway 1 S

St Augustine, FL 32086

3.24 ac · Built 1983

Scott Tr

MLS #GC536645, COLDWELL BANKER COMMERCIAL PREMIER PROPERTIES.

Listing provided by Stellar MLS

4129 United Ave, FL4129 United Ave, FL
Stellar MLS
ActiveOffice360°

$325K /mo

4129 United Ave

Mount Dora, FL 32757

9,835 SF · 1.56 ac · Built 2002

Bennett Sub

MLS #G5103078, COLDWELL BANKER VANGUARD EDGE.

Listing provided by Stellar MLS

1 Calle 1, PR1 Calle 1, PR
Stellar MLS
ActiveOffice360°

$308K /mo

1 Calle 1

Guaynabo, PR 00966

2.1 ac · Built 1990

Colgate - Palmolive Building

MLS #PR9118210, WINER PROPERTY GROUP.

Listing provided by Stellar MLS

910 Old Camp Rd #110, FL910 Old Camp Rd #110, FL
Stellar MLS
ActiveMedical Office

$300K /mo

910 Old Camp Rd #110

The Villages, FL 32162

11,798 SF · 0.34 ac · Built 2007

MLS #G5114135, GRIZZARD COMMERCIAL REALESTATE.

Listing provided by Stellar MLS

225 E Robinson St, FL225 E Robinson St, FL
Stellar MLS
ActiveOffice360°

$267K /mo

225 E Robinson St

Orlando, FL 32801

242,174 SF · 2 ac · Built 1985

Speirs Add

MLS #O6302423, COMMERCIAL REAL ESTATE PROF IN.

Listing provided by Stellar MLS

1255 Cleveland St #400, FL1255 Cleveland St #400, FL
Stellar MLS
ActiveOffice360°

$265K /mo

1255 Cleveland St #400

Clearwater, FL 33755

49,592 SF · 1.7 ac · Built 1968

Hibiscus Gardens

MLS #TB8448134, ONEIL COMMERCIAL ADVISORS.

Listing provided by Stellar MLS

189 S Orange Ave #1430,1450,1470, FL189 S Orange Ave #1430,1450,1470, FL
Stellar MLS
ActiveOffice360°

$255K /mo

189 S Orange Ave #1430,1450,1470

Orlando, FL 32801

9,817 SF · 0.06 ac · Built 2007

Plaza South Tower Comm

MLS #O6358869, ALPHA EQUITY REALTY & MANAGEMENT INC.

Listing provided by Stellar MLS

1 Hammock Beach Pkwy, FL1 Hammock Beach Pkwy, FL
Stellar MLS
ActiveOffice360°

$249K /mo

1 Hammock Beach Pkwy

Palm Coast, FL 32137

25,834 SF · 2.2 ac · Built 2003

Ocean Hammock Prcl B-3

MLS #FC310234, PARKSIDE REALTY GROUP.

Listing provided by Stellar MLS

7200 Lake Ellenor Dr #130, FL7200 Lake Ellenor Dr #130, FL
Stellar MLS
ActiveOffice360°

$229K /mo

7200 Lake Ellenor Dr #130

Orlando, FL 32809

9,100 SF · 6.65 ac · Built 1973

Orlando Central Park 01

MLS #O6370496, ELITE GLOBAL REAL ESTATE LLC.

Listing provided by Stellar MLS

2228 Winter Woods Blvd Blvd, FL
Stellar MLS
ActiveOffice

$227K /mo

2228 Winter Woods Blvd Blvd

Winter Park, FL 32792

2.02 ac · Built 1974

MLS #R4906706, RS EQUITY SERVICE LLC.

Listing provided by Stellar MLS

Listings courtesy of Stellar MLS as distributed by MLS GRID. Data deemed reliable but not guaranteed.

Office Buyer FAQ

What does office space cost in the Orlando market?

Pricing spans owner-user professional condos in the low-to-mid six figures up to multi-tenant Class A buildings in the millions. The live listings above show current asking prices; cap rates on leased office in Central Florida generally run wider than retail or industrial, reflecting tenant and vacancy risk.

Should I buy office space or lease it?

Owner-users with stable headcount often buy to fix occupancy cost and build equity (frequently via SBA 504 financing); tenants who expect to grow or relocate usually lease for flexibility. Toggle between For Sale and For Lease above to compare both against the same submarkets.

Is medical office a better hold than general office?

Medical office tends to carry stickier tenants, higher buildout investment, and lower vacancy than commodity office, which is why it often trades at tighter cap rates. We surface both here so you can weigh the spread on real inventory.

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